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Calorie-dense, highly palatable foods like fried foods, sweets, and fast food become less appealing

It is crucial to understand that semaglutide's effects on insulin resistance are largely mediated through weight reduction and improved glycemic control rather than direct insulin-sensitizing action like metformin or thiazolidinediones

Great sources include apples, bananas, oats, nuts, and sweet potatoes

The study utilized advanced multi-omics approaches, including single-cell RNA sequencing of the heart and liver, as well as cardiac, hepatic and plasma proteomics, to explore underlying mechanisms

The key requirement is that the compound must not be essentially a copy of a commercially available drug