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For repeated blood samples, matched samples were compared using a Wilcoxon signed-rank test

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The total cost of 72 weeks of tirzepatide treatment was estimated to be about $17,500 compared to $22,800 for 68 weeks of semaglutide

Presence, activity and properties of glutaredoxins are often analysed in coupled spectrophotometric reductive assays with bis(2-hydroxyethyl)disulfide (HEDS) as a non-glutathione substrate 10,11,12,15,16,17,18 or L-cysteine-glutathione disulfide (GSSCys) as a glutathionylated substrate 10,11,12,18,19,20,21 (Fig