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Proline metabolism and cancer: emerging links to glutamine and collagen
The scientific focus is clear: rational carrier design, controlled release kinetics, and rigorous characterization must align to translate these platforms from formulation concept to clinical reality
Treatment of diabetes and diabetic complications with a ketogenic diet
Conceptually related to our two-component prodrug, these systems likewise involve separate administration of two elements: a trigger that preferentially accumulate in tumours, and a latent effector to be rendered active by the trigger through specific bond formation or cleavage
Nat Rev Mol Cell Biol 22(4):266282
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