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With extended usability of up to 28 days after first puncture when stored and handled correctly, it offers a practical solution without compromising on safety or performance

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A second interface between the CNS and periphery, formed by the epithelial cells of the choroid plexus facing the CSF, the CSF per se , and the highly permeable ependyma in the brain ventricles, constitute the BCB (Abbott et al., 2010