Published stability data (Lougheed et al., Journal of Pharmaceutical Sciences 2022) show that semaglutide in bacteriostatic water retains greater than 95% potency for 56 days at 5C, but real-world contamination risk increases after 28 days
In a clinical trial in pediatric patients aged 12 years and older with normal baseline heart rate, more patients treated with WEGOVY injection compared to placebo had maximum changes in heart rate of 20 bpm or more (54% versus 39%) [see Adverse Reactions (6.1)]
The FDA labeling documents gastrointestinal adverse effects broadlyincluding nausea (occurring in 1544% of patients depending on dose and indication), vomiting, diarrhea, abdominal pain, and constipation
Jing Guo, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
If your medication appears abnormal, do not use it