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2 As an incretin, GLP-1 regulates post-prandial glucose levels
This is due to the long half-life of oral semaglutide of approximately 1 week, leading to overlap in exposure from consecutive doses during once-daily dosing
Expression of the GLP-1 receptor is widely detected in various cells besides pancreatic beta-cells, such as in neurons, astrocytes, and microglia, suggesting that GLP-1 might have a neuroprotective role 11
That approval means its safety, dosing, and manufacturing have been scrutinized through the full regulatory gauntlet
There is no laboratory test to confirm drug-induced hyperhidrosis
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