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Mounjaro was first approved by the FDA in May 2022 to treat type 2 diabetes, and Zepbound was approved by the FDA in November 2023 for long-term weight loss in adults with both obesity and either diabetes or an increased risk for a cardiovascular condition

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Both fibroblasts and immune cells appear to migrate to the site of tissue injury, whereby fibroblasts promote the formation of an extracellular matrix

Selective fat targeting: Some evidence suggests AOD 9604 preferentially targets visceral fat (the dangerous fat around your organs) over subcutaneous fat (under your skin)

The Lau monotherapy data cuts through that by showing the amylin analog producing double-digit weight loss entirely on its own, which is the cleanest argument that adding it to a triple agonist brings genuinely additive firepower rather than redundant signalling