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Clin Gastroenterol Hepatol (2003) 1(4):26472.10.1053/S1542-3565(03)00130-7 43 Delgado-ArosSKimDYBurtonDDThomfordeGMStephensDBrinkmannBHet alEffect of GLP-1 on gastric volume, emptying, maximum volume ingested, and postprandial symptoms in humans
Trying to escalate every two or three weeks, even if you feel fine, defeats the purpose of titration and significantly increases your risk of gastrointestinal side effects
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In accordance, SGLT2i inhibit renal glucose reabsorption, ameliorating blood glucose levels with additional effects on body weight and blood pressure, leading to improved renal and CV outcomes in subjects with T2DM, especially heart failure and kidney failure [126-131]
Aitken M et al
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