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Researchers tested this on human skin too
Most human studies used it around 2% (as Glutathione or Glutathione Disulfide) and a 2% oxidized glutathione lotion and a 2% S-acyl glutathione cream are the concentrations with actual clinical data behind them
Corrects glutathione deficiencies (associated with aging)
A 1987 study on mice determined oral glutathione to be nontoxic,27 and a 2017 toxicity study (also on mice) found that glutathione's LD (the amount of a substance needed to kill 50% of all test animals in one dose) was 5g/kg.6 An equivalent toxic dose for an 80kg human would be 32.5g, which is more than 32 times the highest amounts used in clinical studies
The Glutathione Bioavailability Problem Most Stacks Get Wrong Here's the blunt truth: oral glutathione supplementation faces a massive absorption barrier that most supplement formulations fail to overcome
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