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The results are encouraging, and specialists indicate that additional long-term research is required to comprehensively address the advantages and potential dangers for varied patient groups

The optimal dosing, administration route, and cycling protocol for humans remain uncertain

Cancer cell resistance against the clinically investigated thiosemicarbazone COTI-2 is based on formation of intracellular copper complex glutathione adducts and ABCC1-mediated efflux

2 There is no evidence regarding dosing, duration, or need for maintenance treatment

This preserves the delicate structure of compounds like peptides for long-term stability