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The high levels of free fatty acids (FFAs) are the main manifestation of obesity
Tirzepatide takes weeks to reach therapeutic blood levels, and the starting dose of 2.5 mg is sub-therapeutic for weight loss in most patients
Continue seizure risk factor screening at each visit, specifically asking about alcohol use patterns, meal skipping, and hydration
The pre-hydration improves blood flow to the oral tissues (good for absorption) while the 5-minute dry period reduces initial saliva dilution
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