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Signal transducer and activator of transcription 3 (STAT3), a crucial cytoplasmic transcription factor in the STAT family, consists of 770 amino acids and possesses a complex domain structure, facilitating its diverse roles in cell signaling and gene regulation (Ma et al., 2020)

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It shows the expected pharmacological response for Fructose ( 5 mM) and exhibits good sensitivity to the GLP-1 (7-36) control (50-100 pM)

doi: 10.1016/j.ejphar.2019.172844 78 HitomiHKiyomotoHNishiyamaA

Obes Facts (2015) 8(6):40224