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Some individuals may experience bleeding during the detoxification process, although this is not a direct effect of detoxing itself

The procedure differs from a subcutaneous injection mainly in depth and needle choice: Select a longer needle (commonly 2225 gauge, 2538 mm) capable of reaching muscle, sized to the individual's tissue thickness

Studies examining cortisol, growth hormone, and other pituitary hormones have generally not demonstrated clinically significant direct effects, though data are limited

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Individuals may experience symptoms such as fatigue (often manifesting as that all too familiar tired but wired feeling), poor quality sleep , as well as a poor ability to handle stress