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Numerous proteolytic enzymes are involved in the GLP-1 peptide degradation pathways 34 and eliminating all possible cleavage sites via amino acid mutation, without dramatically impacting on GLP-1R activity, would be particularly challenging, or indeed may not be possible
The peptides work on different molecular targets while both contributing to angiogenesis through separate pathways
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Chen, Z., Wang, R., Guo, J., & Wang, X
But beyond these metabolic effects, studies have demonstrated that these medications also: Lower blood pressure and cholesterol GLP-1 medications improve lipid profiles by reducing LDL cholesterol and increasing HDL cholesterol, which helps reduce plaque buildup in the arteries
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