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Corticotropin-releasing hormone and the sympathoadrenal system are major mediators in the effects of peripherally administered exendin-4 on the hypothalamic-pituitary-adrenal axis of male rats
Many patients lose a substantial amount of weight while taking tirzepatide, which may help explain the observed blood pressure improvements
The bottom line While there are no magic solutions to address the effects of GLP-1 medications, there are strategies to reduce bothersome effects
Additionally, Orforglipron can cause mild side effects like nausea, diarrhea, and stomach pain
One of the key concerns is how Mounjaro may affect the absorption of oral medications due to its action of slowing gastric emptying
