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Activating and inhibitory signaling in mast cells: new opportunities for therapeutic intervention

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In this model, acetyl-l-carnitine administered intraperitoneally (i.p.) at a dose of 100 mg/kg for 14 days reduced hyperalgesia and apoptosis [43, 44]

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Amyloid plaques and tau neurofibrillary tangles are clearly associated with disease 10 , but other misfolded proteins such as alpha-synuclein (SYN) and TDP43 have also been found to be elevated in the brain of AD patients 11,12,13,14

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