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However, meaningful, clinically significant weight loss typically defined as 5% of baseline body weight, a threshold referenced in NICE guidance on the management of overweight and obesity generally becomes apparent between weeks 8 and 12 , particularly as the dose is gradually escalated according to the trial protocol

National Library of Medicine maintains ClinicalTrials.gov, a searchable database of all ongoing studies

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While patients typically experience efficient weight loss, they might feel lethargic and fatigued while taking the medication because of GI side effects and reduced calorie intake

You have specific dietary needs (celiac disease, severe food allergies, religious dietary requirements) that the limited ASCEND product line cannot accommodate