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Additionally, for diabetic patients, the difficulty in managing blood sugar levels can lead to acute complications such as diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS), both of which can be fatal if not promptly treated
During the initial screening of titles and abstracts, 894 articles were excluded due to irrelevance to the study objectives
Observed Heart Rate Changes: Increase of 5-10 beats per minute during treatment Peak increase around week 24, then gradual decline Persists but diminishes through week 68 Why This Happens: Sympathetic nervous system activation Increased metabolic rate from weight loss Direct effects on cardiac tissue Clinical Significance: Modest heart rate increases (5-10 bpm) don't appear harmful in clinical trials
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L., Hokama, J
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