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Inconsistent administration Skipping doses, irregular timing, and forgotten applications all reduce effectiveness
In vivo, Ex-4 has been demonstrated to inhibit prostate cancer cell growth by activating GLP-1R, reducing s-phase kinase-associated protein-2 (SKP2) gene expression, subsequently increasing p27Kip1 (p27) protein levels, and inducing tumor cell cycle arrest [67]
Figure 7 Effect of SURM on pro-inflammatory cytokines and MAPK/NF-B pathway in the thalamus of RIFM rats
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