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These agents offer similar mechanisms of action with proven cardiovascular benefits and some renal benefits, though SGLT2 inhibitors have stronger evidence for kidney outcomes

Monitoring Is Not Optional The fourth principle is that this level of biological ambition requires a correspondingly rigorous approach to monitoring

This is a common concern, and the clinical reality is that without a maintenance phase, some weight regain is possible because the bodys natural hunger signals will return

Some people may experience more severe constipation that lasts longer

There was no increased incidence of pancreatic or thyroid cancers, acute pancreatitis, severe hypoglycemia, or retinopathy