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( C ) Seahorse XFe24 traces of glucose oxidation, measured as the OCR by sequential injection of 20 mM glucose, 1 M oligomycin, 1 M FCCP [carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone], 1 M rotenone, and 2 M antimycin A into caSMCs cultured in normal (5.5 mmol/L) glucose media

However, like any treatment, they come with considerations that are carefully managed in a clinical setting: Allergic Reactions: While rare, there is always a possibility of an allergic reaction to any substance introduced into the body

Secondary outcomes Secondary outcomes included non-motor symptoms of PD as measured by the Non-Motor Symptoms Scale (NMSS), quality of life of PD patients as measured by the Parkinsons Disease Questionnaire (PDQ)39, and changes in levodopa equivalent doses (LED) from baseline to endpoints

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