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Thus GPX4 may have an important role in the development of PD pathology

doi: 10.1096/fj.202501993r 116 ZhangYHZhangYQGuoCCWangLKCuiYJDongJJet al

Mechanistically, IGFBP-2 can activate STAT3 to increase the transcriptional activity of C-X-C motif ligand 1 (CXCL1), thereby increasing the intracellular expression level of CXCL1, which contributes to the survival of lung cancer cells in the gefitinib environment (136)