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NNMT uses up nicotinamide by tagging it with a methyl group (a process called methylation) and sending it out as waste
Overdoing it can occasionally lead to side effects like nerve irritation (with too much B6), skin flushing (from high-dose B3), or digestive upset
This vitamin is involved in forming DNA and red blood cells, as well as necessary for brain function, heart health, energy production, and more ( Its found naturally in many animal products and sometimes added to fortified foods ( Vegans, vegetarians, older adults, and people with digestive issues that can interfere with nutrient absorption may be at a higher risk of vitamin B12 deficiency and need to supplement ( summary Vitamin B12 is a water-soluble vitamin involved in several aspects of health, including DNA synthesis, red blood cell formation, and brain function
Brand-name semaglutide plus separate b12 supplementation This represents the most straightforward alternative
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