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If Cosmetic Irritation Occurs Reduce cosmetic application frequency Lower formulation concentration Discontinue cosmetic use if irritation persists Cosmetic Application Considerations Patch testing is recommended before larger cosmetic application areas Avoid direct contact with eyes Avoid application to broken, compromised, or irritated skin Lower introductory concentrations are commonly preferred for sensitive-skin formulations For Cosmetic Formulation and Research Use Only Not for injection or human consumption

Less Common Vomiting Headache These typically resolve with continued use or dose adjustment

Without the need for reconstitution, it makes lab preparation for intranasal research easier

Documentation:Vendor COA with HPLC purity and mass verification where available

doi:10.1007/s12178-025-09990-7 US Food and Drug Administration