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By 8 to 12 hours, a significant portion of the medication's appetite-suppressing power is lost, meaning your injection delivers a weaker dose than expected

Typical Dosage The recommended dosage varies depending on individual needs, but a common regimen is a weekly injection containing 1,000 mcg of Vitamin B12

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Key points Obesity is a risk factor for developing osteoarthritis (OA), gout, rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), and is associated with higher disease activity and/or severity, and worse response to common treatments