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(153) identified lactate, hippuric acid, urea, and glutamine as the most important non-invasive early diagnostic biomarkers through meta-analysis

Tirzepatide holds FDA approvals as Mounjaro for type 2 diabetes (2022) and as Zepbound for chronic weight management (2023) and for moderate-to-severe obstructive sleep apnea (2024), and it is EMA-approved as well

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in the economically developed world, however, the widespread availability and the absence of overt deficiency states give little cause for most individuals and their caregivers to pay attention to these potentially pathophysiologic vulnerabilities [4]

10, May 2019, p