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Another study also indicated that exendin-4 improved memory impairment by dampening the AMPK/NF-B pathway, reducing levels of IL-1 and TNF-, and increasing synaptic protein levels (118)
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"Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity"
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However, the study included a small number of participants and a shorter follow up time of only 48 weeks compared to other RCTs studying GLP-1 agonists
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