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Key Research Characteristics Modified IGF-1 analog Extended half-life research compound Reduced binding to IGF-binding proteins Enhanced bioavailability investigations IGF-1 receptor activation research Anabolic-signalling research Recovery and tissue-support studies Potential Benefits in Research Enhanced anabolic signalling research Protein-synthesis investigations Muscle-growth pathway research Recovery and repair studies Tissue-support research Metabolic-function investigations Body-composition studies Nutrient-utilisation research Growth-factor signalling studies Cellular-growth pathway research Extended bioavailability compared with native IGF-1 IGF-1 receptor activation research Safety Profile Hypoglycaemia or low blood sugar symptoms Dizziness or light-headedness Shakiness or sweating Increased hunger Mild headache Temporary fatigue Injection-site irritation Localised redness or discomfort Individual variability in response Increased risk with higher dosing ranges Blood-glucose fluctuations may occur Conservative dosing is recommended Research-use compound with no approved therapeutic use Research Applications Muscle-growth research Recovery and repair investigations Tissue-regeneration studies Metabolic-function research Body-composition investigations Performance-research protocols Growth-factor pathway studies Research Note: The information presented here is based on published scientific literature and research protocols

10.1161/01.CIR.100.22.2248 18

Prevalence of insulin resistance and identifying HOMA1-IR and HOMA2-IR indexes in the Middle Black Sea region of Turkey. African health sciences vol

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They should not be used in people with type 1 diabetes or for the treatment of diabetic ketoacidosis