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The anti-inflammatory properties of glucagon like peptide-1 receptor agonists The glucagon like peptide-1 receptor agonists (GLP-1 RAs) are a glucose-lowering class of drugs that acts by mimicking the native GLP1 action, a peptide hormone synthesized by bowel endocrine L-cells and physiologically degraded by dipeptidyl-peptidase 4
Metabolic alterations mediated by STAT3 promotes drug persistence in CML
DOI: 10.1210/jc.2005-1536 Ionescu M & Frohman LA (2006) Pulsatile Secretion of GH Persists During Continuous Stimulation by CJC-1295 J Clin Endocrinol Metab 91(12):47924797
When viral infections, chronic inflammation, or genetic bottlenecks disrupt mitochondrial function, the body simply cannot produce enough energy to sustain normal physiological processes
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