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Excessive caffeine or energy drinks: Large amounts of caffeine may raise stress hormones and oxidative stress, reducing the effectiveness of supplementation
Having more than that overloads your system with more booze than it can process at once, which is what ultimately causes you to feel drunk and sends your BAC over the legal limit.
Sangpichai et al., 2019)
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The 'superpotent' designation originates from the foundational work by Hadley, Hruby, and colleagues at the University of Arizona in the late 1980s, who demonstrated that Melanotan II induced melanin dispersion in frog (Rana pipiens and Anolis carolinensis) skin bioassays at concentrations 100-1000 fold lower than the native alpha-MSH hormone
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