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The succinylation of LACTB suppresses its own proteolytic activity, leading to an increase in its substrates, such as mitochondrial enzyme phosphatidylserine decarboxylase (PISD), lysophosphatidylethanolamines (LPEs), and phosphatidylethanolamines (PEs) in mitochondria, thereby increasing mitochondrial membrane potential and mitochondrial respiration, enhancing mitochondrial function, and promoting the progression of HCC [81]
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J Fluoresc 30 , 773785 (2020)
Cas9 expression was induced with doxycycline at 0.4 g ml 1 (PanReac AppliChem)
The cAMPPKAHSL pathway can guide experimental design, but each step must be measured before it is assigned to AOD9604
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