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Metformin and fixed-dose combinations were the most common GLDs in DNHR (76.4%), PHARMO (80.9%), and CDM (52.6%), whereas dipeptidyl peptidase-4 inhibitor (DPP-4) was most common in JCKD-DB-Ex (77.5%)

Serine proteases are grouped into 43 families

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Nevola R, Epifani R, Imbriani S, et al

in this situation, NAC reduces the risk of hepatotoxicity to 100 mg/L, the presence of renal failure or ARDS, or progression of the toxidrome despite alkalinization therapy (39)