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ODR10 activation follows the canonical GPCR signaling pathway: Upon binding of diacetyl, ODR10 leads to the dissociation of the trimeric G protein, where the G subunit stimulates opening of TRPV channels (Fig 1A), possibly via polyunsaturated fatty acids (KahnKirby et al , 2004

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Reduced Inflammation Emerging research suggests GLP-1 therapies may help reduce chronic inflammation associated with metabolic disease

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