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Blood samples were collected from dogs administered multiple doses at corresponding time points before the first dosing (0 h), within 6 h after dosing, before the last three doses, and at corresponding time points after the last dosing

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doi:10.1007/s40268-015-0119-3 Caudal route: This is a general approach is simple to administer, but medication doesnt go directly to the source of the pain in the epidural space and around the nerves