Academic and industry research consistently shows that first-to-file generics can generate 60-80% of a products total generic market profit during the exclusivity period, because they can price at 10-20% below the brand rather than the 70-90% discounts that become necessary once five or more generics enter the market simultaneously
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus (Mounjaro) and chronic weight management (Zepbound)
The Phase 2 trial data was striking
Biolo, G., Stulle, M., Bianco, F., Mengozzi, G., Barazzoni, R., Vasile, A., Panzetta, G., and Guarnieri, G
Individuals with obesity should be counselled to accumulate at least 150 minutes a week of moderate aerobic exercise, such as walking, and to engage in resistance training to preserve lean mass