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Patients were randomized to receive either weekly subcutaneous semaglutide 2.4 mg or placebo, with the dose gradually increased over 16 weeks to minimize gastrointestinal side effects

The pharmaceutical company highlights that both primary endpoints were to demonstrate that oral Foundayo or Zepbound continuation at either the reduced dose or MTD was superior to placebo in maintaining body weight reduction

For patients who have a history of gastrointestinal intolerance, an alternative incretin-based therapy may be preferred over Semaglutide (Nathan and Group, 2014

Another new compound making big promises

& Harrison, D