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Not all patients are candidates for GLP-1 treatment

There is interest in the idea of prescribing them to people with good metabolic health to prevent future complications, but current clinical evidence to support this method is lacking

Neurological symptoms are among the most clinically significant and may include: Tingling, numbness, or a 'pins and needles' sensation in the hands and feet Difficulty with balance and coordination (sensory ataxia) Memory problems, cognitive slowing, or confusion Mood changes, including low mood or irritability Haematological symptoms may include: Persistent fatigue and weakness Breathlessness on exertion Pallor or a slightly yellowish tinge to the skin A sore, inflamed tongue (glossitis) It is worth emphasising that neurological damage from B12 deficiency including subacute combined degeneration of the spinal cord can progress and become irreversible if treatment is delayed, even in cases where anaemia is absent

Diagnosed with pre-diabetes, he was desperate for a solution

Clinical trial data shows patients typically lose 5-10 pounds total by week eight, with momentum accelerating if dose escalation occurs