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K cells are responsible for the production of GIP and the L cells for GLP-1

For an orthopedic surgeon, this is relevant because muscle mass is a primary driver of joint stability, injury prevention, and post-surgical recovery

This modification enhances its biological activity, resulting in a higher affinity for the IGF-1 receptor and a lower affinity for IGF-binding proteins compared to endogenous IGF-1

This is likely due to their role in dampening the brains reward circuits

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