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For instance, when peripheral tissues become inflamed, the related signals might be transmitted to the brain through these receptors on the neurons, and the brain could then respond to these signals via neural pathways, thus regulating the level of peripheral inflammation

In animal wound models, it accelerated healing and reduced inflammation, suggesting applications for joint, tendon, and soft-tissue repair

The general rule in dermal pharmacology is that molecules above 500 daltons penetrate the intact stratum corneum poorly (the "500-dalton rule" described by Bos and Meinardi in 2000, Experimental Dermatology )

Injection quantities vary per individual purpose