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Here, we provide the first evidence of delayed aging with a therapeutic mAb, via long-term modulation of IGF-1 action

( i ) Quantification of H2AX foci in cells expressing empty vector or CCNE1 transduced with shRNAs targeting TMLHE alone (shTMLHE) or supplemented with propionylcarnitine or butyrylcarnitine (n = 3 technical replicates representative from 2 independent experiments in each cell line)

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However, stress, pollution, smoking, toxins, poor diet, inflammation, and ageing can increase their production

What is Gene Modulation