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Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

A major meta-analysis finds that patients who discontinue anti-obesity medications quickly regain weight, yet, crucially, they still retain some of their original weight loss a year later, spotlighting the challenges and promise of long-term obesity treatment

It stimulates both collagen and elastin production, addressing the structural changes underlying most visible signs of aging: fine lines, wrinkles, loss of firmness, and skin thinning

10.1167/iovs.19-27939 185 WangD.LiuQ.WuD.HeB.LiJ.MaoC.et al (2018)

Rapid weight loss, dehydration, and changes in fat metabolism can temporarily stress the liver in some cases