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A plausible Nobel citation: For discoveries establishing GLP-1 as an incretin hormone and enabling GLP-1-based treatment of diabetes and obesity. If the award arrives in 2026, I will not be shocked
Semaglutide is less effective at reducing body weight in T2D patients compared to patients without (5% weight loss, SUSTAIN-6 and 15% weight loss, STEP, respectively)
Furthermore, GLP-1r / mice had an enhanced level of urinary DPD, which indicated increased bone resorption
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The drop works in a similar manner as natural hormones that regulate appetite and hunger
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