Ignoring diet quality Taking a probiotic while eating a diet devoid of fiber and rich in processed foods is self-defeating
PLoS Pathog (2015) 11(7):e1004903.10.1371/journal.ppat.1004903 178 ReijndersDGoossensGHHermesGDNeisEPvan der BeekCMMostJet alEffects of gut microbiota manipulation by antibiotics on host metabolism in obese humans: a randomized double-blind placebo-controlled trial
As early as the mid-20th century, studies of commercial diet programs showed that while short-term weight loss was common, regaining weight long term was the norm
Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome
Further, studies are linking the consumption of artificial sweeteners with pathogenicity (Shil and Chichger, 2021), sucralose with genotoxicity (Schiffman et al, 2023), and aspartame with neurotoxicity and cancer (Shaher et al, 2023)