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Tretinoin already turns over the top skin layer fast

But they can temporarily improve the skins appearance by increasing hydration, smoothing the texture and supporting collagen production, says Engelman

Rather than focusing solely on weight or body mass index, researchers increasingly argue that body composition measures, such as the proportion of fat mass and lean mass, provide more meaningful insight into treatment effectiveness and overall health outcomes for people living with obesity

For others, especially those losing substantial weight quickly, periods may become lighter, irregular, or temporarily ceasea condition called hypothalamic amenorrhea