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Monitoring: Patients with recurrent infections (three or more episodes per year, per CDC definition) require further evaluation to identify underlying causes, which may include uncontrolled diabetes, immunosuppression, or non-albicans Candida species that may require culture and susceptibility testing
The FDA mandates prescriber oversight for any medication that alters these physiological processes, since individual health statusincluding kidney function, pancreatitis history, and medication interactionsmust be evaluated beforehand
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Goldspinks laboratory at the Medical College of Wisconsin has specifically characterised IGF-1 isoform activity in cardiac tissue, demonstrating MGFs role in preventing cardiomyocyte death, preserving contractility, and preventing pathological hypertrophy following myocardial infarction in animal studies
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