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Novo Nordisk first developed semaglutide for type 2 diabetes (Ozempic, FDA-approved 2017) and later for chronic weight management (Wegovy, 2021)
Weight cycling is a repetitive pattern of gaining and losing weight
It works by mimicking two gut hormones, GLP-1 and GIP, that communicate with the brains appetite centre (the hypothalamus) to reduce hunger and food-seeking behaviour
Figure 3 As mentioned previously, GSH, a tripeptide containing glutamate, cysteine and glycine, (L--glutamyl-L-cysteinyl-glycine) is the master and most potent cellular antioxidant and the most abundant low molecular weight thiol that plays a crucial role in antioxidant defense against cellular ROS/reactive nitrogen species (RNS)-mediated oxidative damage and in the regulation of numerous metabolic pathways essential for maintaining whole body homeostasis
Patients should avoid injecting into areas with scarring, bruising, or skin problems
