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Your peptide-pathway geneticsthe DNA variations that influence how efficiently your body signals fullness, burns fat, and regulates appetite hormonesdetermine your individual therapeutic window
Combination with other agents might allow dose reduction of the GLP-1 component
One of the biggest problems is discriminating true signal generated by target molecules versus non-specific background
One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes
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