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Severe nausea requiring treatment discontinuation was rare in monotherapy trials, with only about 1% of participants in the REDEFINE 1 trial stopping treatment because of adverse events overall
doi: 10.1056/NEJM199503093321001 24 SumithranPPrendergastLADelbridgeEPurcellKShulkesAKriketosAet al
Healthcare providers must weigh the severity of the deficiency against the patients overall health
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