Nevertheless, by using a functional bioluminescence resonance energy transfer (BRET) technique, we could not find significant differences in the ability of the D 4.2 R, D 4.4 R or D 4.7 R polymorphic variants to promote dopamine-induced activation of any of the five Gi/o protein subtypes (35)
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Its small size may make it particularly useful for localized topical formulations
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