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[5] In Latin America, about 40 percent are estimated to be affected, and this may be as high as 80 percent in parts of Africa and Asia
However, without continued NNMT inhibition, some metabolic advantages will diminish over time
[1] Independent groups have since reported other chemical classes of NNMT inhibitor with metabolic effects in obese mice, reinforcing NNMT as a genuine metabolic target
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